Found
this thread. Problem is there are many issues that can cause the vibration you describe, driveshaft is only one of them. I would take it for another test drive on concrete vs asphalt as described below, and if possible, put some weight in the bed and see if it goes away. If it is beam shake, you might get the dealer to put on the revised body mounts as part of the sale (assuming you are buying from a dealer). If it's not beam shake, then you have a "fixable" problem that should be addressed before you take delivery.
I wouldn't steer away from the truck if all else is OK, just know what you're dealing with before you sign on the dotted line.
GM Campaign #PIT3009J: Suspension Vibration Or Frame Beaming At 40-60 MPH (64-80KM/H) - keywords front rear shake shock spring tire - (Sept 18,2008)""
Condition/Concern:
Beam shake vibration is usually felt and occurring at speeds between 40-50 mph (64-80 km/h). Hertz readings using an EVA tool are normally bewtween 8-24 HZ. This condition is most common on extended cab and crew cab models but has also been noted in other models.
Recommendation/Instructions:
The severity of the beam shake may vary from vehicle to vehicle. To determine if the concern is beam shake, please perform the following:
1. Test drive vehicle to confirm the condition. A beam shake condition will usually respond to concrete type pavements more than asphalt, so the vehicle should be driven over both surfaces if possible.
2. Place 200-500 pounds in the pickup bed between the closed tailgate and the wheel wells. A beaming condition should dissipate.
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If the concern is determined to be beam shake, this a characteristic of the vehicle. GM Engineering has released updated body mounts to reduce this concern for the Crew and Extended Cab Models. There will be no changes made to the Regular Cab Models.