I'm not completely against the idea of a dually, I'd just like to avoid it if at all possible. Something in the middle of that I'd say(I'm going to try to get my wife in the absolute smallest thing I can, with two young kids...), certainly no slides. I really want a hard side anyways. Like I said if those giant expedition vehicles can make it down the pan american than so can a dually truck camper. People do it in anything from a two wheel drive car to school buses to 18 wheelers. So I can't go everywhere a Land Cruiser with a tent can go, big deal, I need my family to be comfortable. There'll be plenty to see, just as there is plenty to see in my 35 ft fifth wheel.
Also thanks for the info on the flatbed and the standard utility body thing(we're going to have some type of bathroom for sure), that's really usefully information for me.