Disadvantages of running a 65PSI vs 80PSI E Tire?

I’m assuming the question is what is better if both have the same capacity, but one is 65 and one is 80. My guess is that the tire with 80 will ride rougher and have slightly less sway due to having more air in the tire. However, it could work out different if the reason why the tire is 65 and the same load capacity is that it has a stiffer sidewall.

I do know that the same tire with 65 and 80 will ride softer at 65. I’ve tried that.