I had changed from load range C tires to load range D tires because my tires were seven years old and I had put 18,000 miles on them plus whatever the original owner had on them.
While shopping for tires I noticed that some tire brands had a load rating of D at 65 psi and a load rating of C at 55 psi. The objective was to match the tire pressure to the load rating for the best performance.
I bought D rated tires and ran them at 65 psi but soon discovered that the trailer contents were being battered by the harsh ride. I now run them at 60 psi.
Some folks run at maximum pressure with no difficulty.
The week link in the system is the TT axel rating, you have to look at your TT axel rating and decide how much over that you want your tires rated for.