It's pretty obvious that truck frames aren't that strong to begin with. It would be possible to have a stronger frame after modification with proper technique. But then, you need a different bed and drive shaft as well, and who knows if it would turn very well. I'm thinking it would be pretty bad.
I have no idea why it would be worth it to carry a TC. Other than the Megacab for the Rams, I can't see the application at all. The rest of the trucks come with long beds in the biggest cabs.
I've also seen lowered DRWs. I'm not really sure that people do with those either, but whatever floats your boat. :)