Aaaaaaaaaaaa the OP has a Duramax not a gas rig.
No I don't use additive in any of my diesels and haven't since I owned any of them. Most of them have mostly kerosene in them anyway. Make sure this stuff has no alky in the mix. Some do and that is BAD news for a diesel engine.
As far as alky in gas engines go. Alky has WAY less BTU's and you will NEVER get better mileage to do the same job as straight gasoline.