I'm trying to find the links to some studies that demonstrated that tiny mesh screens impede airflow, not only by the summation of the free hole area, but also by other aerodynamic effects that disturb the flow through the screen.
I understand about the bugs and stones beating up the radiator though. Especially with your kind of miles. You probably kill a lot of em. Between dried wings and stone hits, the forward facing surfaces of your heat exchangers might look like the craters of the Moon, with all those miles.
I'll keep looking for those studies (that motivated me to discontinue the use of screens 16 years ago). It's tough trying to find the balance to achieve optimum cooling, bug/stone protection, avoidance of ice damming, etc. That's why I leave all my grilles stock. I already know the OEM's put a fair amount of thought into finding that balance, and I want to cash in on all the engineering I already paid for when I bought the truck.