Your profile says you bought a 5th wheel, but based on your original post, I'm assuming you are considering a travel trailer instead? If I'm wrong, ignore most of my post! :)
You can definitely travel with a TT alone. There are things you can do to make it easier.
Someone mentioned your hitch. That is the heaviest thing you have to handle. There is a carry handle you can buy to carry the hitch around.
Hitch Grip Coupling Tool. I don't have one, but it looks like it would make carrying the hitch much easier.
Here's a video and diagram of how it works.
The spring bars for the hitch are also a little heavy, but I saw someone's post where the bars for a Blue Ox SwayPro are lighter. I don't have any experience other than my own old WDH. The labels are gone off it, so I don't know what brand it is. It came with the trailer. It is the basic spring bars with chains and snap-up brackets.
I hitch and unhitch just fine with my manual tongue jack. It does require some cranking, but that doesn't bother me. If you found a manual jack too difficult, though, an electric jack would be easy to install, and easier to work with.
I bought a mirror from CIPA that works on the back of my Suburban (with the glass door up). It is cheaper and simpler than a backup camera, unless one came installed on your TV. The CIPA mirror I have is
this one. I just slide it down over the lift gate with the window opened. Note: the suction cups don't work. They only hold for a couple of seconds on glass, then the mirror falls off.
Use an 18 volt battery drill for your stabilizers. It saves a LOT of cranking. You can just about have all 4 down with the drill before cranking 1 down manually. I forgot my drill on my last trip, and I vowed that would never happen again!
I don't see why you can't do this alone. Of course, you know your limitations infinitely better than I do, but there are definitely things you can do to make it easier. Good luck.