My truck rides well and handles better now than it did with the 3750 Load range E Toyos. I think it comes down to load and pressure set up. I had no choice but 80psi all around on the Es I run 85/105 on the 19s which is no where near their max PSI so it doesn't feel like driving on a rock or ice skate.
All I can say is Cat Scale your load then figure out what is going to work for you. There are no simple answers.
I will just put this out. My truck = $50,000 and my TC $30,000 to replace. The sole thing keeping everything on the road is the tires and wheels. I spent the 2k (got a trade in for my existing tires and wheels) to protect the 80k investment. now if you include my family in that figure: priceless. I did almost roll when I had my freeway speed blowout with the E. I don't need that experience ever again.
