I just took delivery of a new F350 diesel. I'm currently working my way through the 600 page owner's manual and also the 100 page diesel supplement so this is fresh in my mind. There is a very clearly worded statement in the manual stating that if you add any type of performance enhancing product (chips, tuners, etc) the computer will know. And it will tattle on you. And this info cannot be erased even if you remove the equipment before taking the vehicle in for service or repair. The clear implication to me is that Ford will blame any failed drivetrain components on those mods (if you do them). I assume that GM and Ram have the same sort of verbiage in their owner's manuals. To me, it's just not worth the risk. And I do realize the OP is not talking about diesels. But an engine is an engine.