We have our camper permanently stationed at a campground four hours south of us in Valdosta, GA. We have a son who lives there, and it's SO nice to be able to get there and not have to load/haul the camper to that campground after work for a weekend when we visit him monthly. It's also on the way (sort of) to many of the campgrounds we like to camp at in FL, so it's not a problem to pick it up and continue on to another destination. It saves us gas money not having to tow the camper as far, as well as time, since we drive faster when not towing.
A drawback is that we now cannot easily camp in the mountains a little north of us. In a perfect world, we'd love to have two campers; one to keep in Valdosta, and another one to take camping to non-FL destinations. Maybe eventually...