Using that "logic" one would want to get rid of the fridge vent, the A/C unit(s) and the black and grey tank vents, then you have zero holes to deal with..
Reality, however, properly done your roof vents pose no more problem for future leaks than the trim that covers the roof to side wall..
Not to mention then you would have the ugly openings on the inside where the roof vents used to be that you would have to cover up..
I do use the roof vent in the bathroom when taking a bath, I did eliminate the roof vent over our master bed when we rebuilt our TT, wasn't a fan of the light that came through it early in the morning at the crack of 5AM.
It is a personal choice and up to you.