Thoughts on Uneven Tread Wear on 192 RBS?

I did an alignment check a couple years ago on my own 192RBS, not because of uneven tire wear, but because I was surprised to discover the spread between the curb side tires was less than the spread between the street side tires. That spread would also vary somewhat depending on how much lift I had to do on either side in order to level the trailer side-to-side. All measurements proved to be exactly what they should be, then I realized axle spread will vary because the trailer weighs more on one side than the other. That only became apparent when I was having a difficult time fitting a pair of BAL Standard Tire Locking Chocks between the tires, a problem I've since solved by trimming the chocks. Having recently had one of my own stock off shore tires split for no apparent reason I'd suggest Last Train replace all four tires now and just keep an eye out for any signs of unusual wear in the future.