I had a set of Maxxis and was happy with how they performed. When I went to replace them I was pointed in the direction of the new Carlisle HD tires. I went with a load range E, up from a D, and they ended up costing less than an LRD Maxxi would have run.
Check the maximum weight rating for your trailer and then look at the max rating for the tires you are looking at. Multiply this number by 4 and see if it will cover the weight of your trailer. I also suggest that you have a healthy margin above the trailer weight. Someone said 15%.
The Carlisle is rated at 80mph which I will never get close to. It is nice to have a tire I can exceed 65 though, if only once in a while.