Buzzcut1 wrote:
Me on I5 in the central Valley passing a semi at 65. I was running Toyo Open Country tires 285/75R16 rated at 3750 I was right at the tire rating and I had a belt separation. The left rear tire shredded almost instantly. I fought for control to keep from rolling and to get to the shoulder safely. I upgraded to 19.5s after that just for the peace of mind. rig was a 2003 F350 CC SRW Longbed 4x4 carrying a Lance 1055

I had exact separation while driving empty on my F250, but that was "famous" Firestone tires who had whole list of recalls.
If you study the tires - they can easy take 3 times the rated load when rolling.
What kills them is combination of heat and load.
Heavy load with low pressure makes tires flex more than manufacturer design, what generate more heat and heat deteriorates the rubber.
Speed is accelerating factor.
My trucks were used in construction and very often rear tires were overloaded by 20%. But that was on +- 10 miles drives at 50 mph. Never had blown tire is that use.
Remember old El Caminos? I had garbage scale receipt showing 2100 lb cargo on it. Car tires, but El Caminos had factory air-adjustable shocks