Gebrown, welcome to da forum...
first your going to get some flak towing with a lifted truck, then towing a "toy hauler" with a 1/2 ton truck, the forum weight police are gonna be all over you!
second, I pulled a travel trailer with my ole 05 3500 quad cab diesel, that had 6" of lift and 37" tires! was very stable contrary to what others (whom most likely never driven on anything larger then OEM size tires) may say about large diameter tires. So, pulling any trailer with your "lifted/over sized tires" will not be an issue, as stated in 2nd post... its going to depend on trailer weight, length and type.