I don't think GM has an OEM isolator as standard EQ. in their trucks, even with a tow pack.
If your style is to park for long periods of time while still being hooked up (TT to TV ) , you should have an isolator solenoid installed under the hood, they are not expensive .
Isolate your TV starting battery from your TT deep cycle battery, so you don't run them both down and not be able to start the truck.
Without one, you have to unplug the TT from the TV and remember to plug it back in before you drive off .