No worries .
I would upgrade the 4 tires on the ground .
I would leave the spare the same
I upgraded my tires on my 1997 Vortec 7400 chevy right away to 265/75R16 load range e from the stock 245/75R16LRE stockers .
I did the same on my 2002 duramax .
I used my spare one time in those 17 years .
I credit the tough load range E cords for not allowing easy penetration of road hazards .
Four tires rated at 3415 # each for a pickup rated at 9200 # gvw is no challenge for the upgraded tires .
The additional surface area decreases the load per square inch on the tires .
So they are less likely to succumb to a road hazard .
The spare on my 2002 duramax has never been on the ground .
I practice and believe in upgrading my pickup , TT , and boat trailer tires .
I never have a flat .