Ultimately there is NOTHING stopping you from putting a TravelLite 625 on a Toyota Tundra. No laws say you can't. No insurance company is going to refuse to sell you coverage. Heck, the RV dealer will happily load it for you; just sign on the dotted line.
CAN all the doom and gloom happen? SURE! Will it? Probably not. That's the truth.
Your truck is not going to fall on a pile the moment the camper touches it. The truck is not going to burst into a huge fireball and take out a busload of orphans and nuns.
It won't handle like a sports car, but unless you are a complete moron, you will compensate by driving slower and allowing yourself more time and space on the road.
Will tires blow, axles break? Maybe, but not right away, and if you keep on top of maintenance, keep good tires on the truck, you can minimize the chances of that happening. Most likely you will not be able to use the camper nearly as much as you'd like to, and what little you get to use the camper will put minimal wear on the truck.
The REAL question you need to ask yourself is, "WILL I BE HAPPY WITH IT?" You're spending $30,000 to $35,000 on a truck and camper here that is hardly ideal on paper. You are taking a HUGE chance that you will *HATE* driving it after the newness wears off.
If you hate it, then what? Glue on some more suspension mods? Take a huge hit and trade something in? Leave it sit and rot in the driveway?
A comfortable rig makes for a comfortable driver. A comfortable driver is a safe driver. Everyone has a different idea of what "comfortable" is. You can take a chance that this "outside the box" combination will suit you. It's your money.