Which hitch setup will work the best?

With an F250, I don't think you need to start thinking about too much hitch. I use a Reese HP trunion style with cams integrated into the 800 lb bars in case I feel the need for sway control sometime down the road. Tongue weight on our TT is advertised at 700 lbs. With all we have in it now, we're probably over 900 lbs tongue weight. Empty, trailer on with or without the spring bars, the front of our F250 doesn't change height. The rear settles two inches without the bars. The spring bars bring it back up one inch. Tows like a champ. The head of the Reese HP is rated for 1700 lbs tongue weight and only the spring bars need to be changed for different tongue weights. What is your receiver rated for with and without the reducer tube?