I've been using the starter solenoid relay for battery isolation and charging on all my tow used vehicles since 1984. Never purchased an off the shelf battery isolator since as that's all they are is a relay at big cost. Installed a 65-8- amp slide switch and a 65-80amp marine fuse before the relay and a 65-80 amp marine fuse on the other end in back of the truck.
Last 2 trucks I also added a lighted on-off control switch next to the RV brake controller under the I/P so I can even control it while driving if desired. The vehicle ignition switch activates the relay instantly when turned on with the key and turns the system off when turning the ignition off. Cheap, very heavy duty, easy to do, and 100% positive!
Have a no. 14 gauge wire with an alligator clip on each end to activate the relay by attaching to a battery + terminal and the + on the relay which couples the 2 group 31 deep cycle batteries (all batteries are except the 2 engine batteries) in the truck's driver's side bed. Or if the TC or 5th wheel is connected with their batteries also, I can easily start the truck's diesel engine anytime or use a 1500 watt + inverter outside right from the truck for a long high wattage draw without even needing to run the truck engine. Couples up to 9 big 12V batteries and the connecting wire cables are no 2 gauge fine strand copper welder wire. 2 batteries in the engine compartment, 2 in the bed, and 5 in the 5th wheel =9. 1 in the TC, 2 in the truck bed, and the 2 for the engine = 5 in that configuration.
Ordered my truck with dual alternators which makes very quick work of recharging batteries if or when needed and because of the very heavy gauge coupling cables used. Little voltage drop!
The OP is doing the smart thing and approach!