160 is an RV pipeline across southern Colorado. Wolf Creek Pass is long an fairly steep, especially eastbound. But two lanes going up so you can stay right, go your comfort speed, and not worry about holding up traffic. And there are guardrails all the way. Going down watch your speed, especially approaching the snow slide shed with a curve inside. Mind the posted speed limit for it.
Then a long flat run across the San Luis Valley before you head toward North La Veta Pass. You might take s side trip to the sand dunes as you pass by them in the valley. North La Veta Pass is steeper going down than up when traveling eastbound. Again, watch your speed as that is again a long grade and easy for your speed to creep up. But very good highway. And there are guardrails.