At the Western port of entry San Ysidro there are 4 distinct and separate areas, left side is the general lanes for just the tourist visas, that take any where from two and a half hours to four hours depending on the agents in the booths, if you get the rookies it takes for ever.
Then come the ready lanes that take the enhanced border crossing cards, those lanes start along the right hand or West direction next to the Rio Tia Juana and are narrow with very sharp and a tight left hand turn just before the border, a 40 foot RV will scrape the concrete barriers, the wait times vary from a half hour to four hours depending on the hour and traffic.
Then come the sentry lanes and they are only for the vehicles that have been pre screened, there again the access is from the river, not recommended the CBP agents get really annoyed at you plus the lanes are really narrow.
Last but not least is the passenger bus lane, access is by the sentry lane right hand lane, this lane can take up to four hours until you reach the CBP booth, then you might end in secondary for another hour plus.
If you have paperwork that needs to be turned in there are no offices at all on the lanes going North to san Diego or anywhere to park or stop, the Banjersito and Immigration offices are on the Mexican entry side and no vehicle access from the lanes entering the USA or for that matter pedestrian access.
Otay Mesa is a commercial entry and they handle all entries as such, Sentry lanes are on the right hand side and all others to the left, the Banjersito office is on Avenida Segunda, you need to navigate the streets if returning paper work, a lot of big rig traffic and hard to get to it the Banjersito and Immigration office is on a dead end street with lots of parked vehicles, turning a big 5th will be a challenge plus there is no where to park on the lanes leading to the border crossing and there is a wire fence at the end of the Segunda AV, wait times for this port of entry are normally a fast two hours and a half hours to four and a half plus, I avoid this entrance at all.
From your post I see that you are familiar with the Tecate entrance, use that crossing and when you get to the 94 "T" instead of going right go left on 94, there are some campgrounds on 94, if you want to go to San Diego keep going there is a Border Patrol inspection station, after the station a couple of miles there is a road just before a bridge on the left, this road is Otay Lakes Road make the left turn, this road takes you in to Chula Vista stay on it DO NOT get on the toll road, continue and you will see the first freeway, the 805 keep going until you get to the I-5 and go North, there is a nice RV park at the marina, if you want to go there get off on "J" street turn left under the freeway keep going the street makes a gentle right turn, at the end of the marina parking lot make a left turn, at the end of the street go right and mid way on the block on the left is the entrance to the RV park.
navegator
