Robby, you did not mention what year your pickup was I'm guessing newer than mine which was one of the first 2011 models. Mine had the tow package that included the 5th wheel prep package. My pickup has the 8 foot bed and the 5th wheel prep package may not be available in the short bed. But if you should have that option you will have 5 holes ( rubber plugs) with in the bed center forming a X. The 5th wheel uses the 4 outside tips of the X, Gooseneck hitch uses the center hole and the forward 2 holes for chain attachment. Reese Hitch is the supplier for Ford.
The nice thing about this arrangement, all the frame is below the bed so if you should remove the hitch you have the flat surface of the bed.
Happy Trails