Good for you, go for it. Living in an RV isn't much different than a home, just smaller. If you need to have a workshop, if you need to clean 3k sq/ft or fill empty space with things to fill your day or have self worth then you might have problems adjusting to the lifestyle.
Otherwise if you have hobbies and can fill your day without needing all that extra space you'll adjust just fine.
Travel nursing is a great way to make money. Just keep in mind many of the places that need travelers and pay well are areas where people generally don't want to work for one reason or another. She'll also be an outsider and will likely get crappy assignments. Still a great way to make some money and see the USA. Just keep it in mind that if she was in her current hospital for x year, traveling will be a big change for her.
2019 Grand Design Momentum 395
2018 Ram 3500 DRW 4.10
2014.5 DRV Atlanta (sold)
2008 Newmar 4330 (Modified) Sold