I agree that it would be very foolish to sell everything and put it all into a plan to RV forever. But that doesn't sound like your situation. Others have mentioned the biggest issue is getting rid of your stuff. That definitely cuts you twice. Selling your belongings will net you a fraction of what you paid for them, is that OK with you? The alternative is storing everything which is expensive and not really good for things in the long run. Then if you decide to stop full timing an move back into a traditional home, you have to buy a lot of that stuff at full price. Not a deal breaker, but it does sometimes make you want to kick the dog.
To me, a house, unless it is something really unique due to location, historical significance etc. is nothing but a collection of 4 walled rooms. If you sell your house, place the proceeds in moderately conservative investments, you will have more than enough money to replace it when you decide to stop the full time lifestyle. On top of that, when you do make that transition, the odds are great that your old home would not be exactly what you would want or need. If that is the case, selling now may be an advantage.
As for full timing, it can be exciting and rewarding, but you do give up a lot you might currently take for granted. Gardening, your church, your weekend football buddies, the routines you have, will all change or disappear. Many people find that the square footage of a RV is fine for a weekend, but leads to homicidal rage over months and years.
Your post indicates you have the ability to "try it before you buy it". That is heck of a good plan. But to make it a true test, include a couple of months not in the prime of what you expect to do so you can get a feeling for the down time.
