Having owned a 33' 5th wheel(5 yrs) before our coach I could never go back. Had no complaints whatsoever with the ride of our pickup with the trailer but the Motorhome is so much nicer. I'd have to have a Mobile Suites 5th wheel to be even close but then I'd be cruising around in a dually which would not be the ideal vehicle to see the sites.
Love site seeing in a smaller more fuel efficient vehicle, maint on new gasser is super cheap amounting to an oil change 1x per year depending on miles, Stays much cleaner with the full body paint, quality way above the trailer, ease of setup, on board generator, storage second to none, having bathroom at our disposal, etc etc.