My personal opinion (please re-read those first 3 words) is that once you get your RV ready to travel you need to fill your tanks with fresh water, ensure your holding tanks are empty and hit the road! Class A RV's are ready to travel in cold weather they just aren't ready to sit, unoccupied, in cold weather. So, if you want to travel from MA to FL all you need to do is go! As mentioned above you do need to check to see if there are campgrounds open where you plan to end your day but, if not, you can always overnight at a Wal-Mart, Flying J, rest area or similar location designed for this kind of an overnight (not camping, but parking overnight). The coach will keep you warm and all of your holding tanks warm so chilly/cold weather should not be an issue. Depending upon the size of your tanks and your ability to conserve water you should be good to go for at least a week and as long as 2 weeks without requiring campground hookups. Since it's unlikely you will have any plans to go that long without finding a campground your trip should be completely uneventful!