We just bought ours in August & got what I consider to be a great deal.... private party to private party (no sales tax). After having purchased 2 brand new RVs at earlier points in my life I resigned myself to not do it again. I prefer to let someone else deal with factory gremlins/warranty & of course the depreciation is brutal.
Every platform has it's pros & cons, including the E350 & V10 units respectively. I don't find either the road manners of the 350 chassis or the noise of the V10 to be show-stoppers by any stretch.
I'm pretty happy with the Itasca/Winnebago build quality when I compare it to multiple other manufacturers' stuff I've owned over the years.
Durability is a huge factor for me. The V10 is a known good/reliable pkg & I like that.
Happy Camping!