Many RVs have different size tires front and rear, so one would be restricted from rotating.
On the other had, I rotate my tires because I have front wheel drive. My fronts wear much faster than the rears, so when they are about half worn, they get moved to the rear and a new set gets put on the front. The rears on mine take for ever to wear, so they get cycled through. I end up buy two tires every third year. This way I can get reasonable traction in the snow.