Wolf Creek pass is not a real problem just as previous poster said you will not get up it in a hurry. It is a bit of long slog up (and what pass in CO isn't) but the road is good. Been over it literally hundreds of times granted mostly in my truck but even with the 5th wheel it is not a problem. Just take your time watch your speed going down. Big trucks and rv's use it everyday. 8ish years ago they added a tunnel on the east side approach that cut out a turn and widened the road to the east it is better than it was long ago. On the east side from the tunnel to treasure falls waterfall at the base of the west side it is 3 lane nice and wide. From Pagosa to west base excellent road. From east tunnel to South Fork is mostly great road a short stretch that is narrower than one might like but it is still plenty good. South Fork to Del Norte is great road. Turn off in Del Norte to catch 285 instead of going to Monte Vista as it will save you about 10 miles and is great road. 285 is fine all the way to Denver.
