battery disconnect are handy for storage situations
BUT
you need to find your problem, start by checking the vent fans are operating, can be turned on off, a failed fan that looks OFF not running might actually be stalled or shorted and using power
next pull all the house DC fuses from the fuse panel
check your battery again the next day, still charged ? then it is one of the fused circuits
put the fuses back in one by one
watch for sparks
fridge ? is it a 3 way, 12v 110v lp,
make sure the 12v option is off
do you have an inverter ? did it get left on ?
truck camper ? trailer ? pop-up ? motorhome ?