Grover,
Based on my 40 years towing etc. Going from a potential high of 26 to 16 mpg and getting 10 towing, is not totally out of the ballpark.
I've gotten upwards of 25-26 with my current 1500 4.3 V6 empty, as low as 11-12 towing. An older GM 6.5 TD 16-18 down into the 11-12 typical, low of 9 best 14 towing multiple factors involved. My Duramax was a bit better than 6.5. BB V8 12 down to 7-8. SB V8's similar to 6.5 TD mpgs. Maybe 1mpg less.
So 40-60% in mpg/driving range is pretty typical. SWAG based on my numbers, some that have posted in last couple hours, a 40-50% drop is more typical for most most of us, with the 45% I mentioned earlier being a reasonable ave drop overall.
Marty