It is somewhat for me...
S.O.B has a truck stop in the back. My brother is a truck driver and told me he stayed there with no issues. Walmart is a little past SOB, that is my backup plan if SOB doesn't work out.
O'man I didn't realize buffalo was so far from Md. You have a nice drive ahead of you.
Google is telling me this:
buffalo new york to maryland
6 hours 59 mins
maryland to south carolina
8 hours 9 mins
south carolina to orlando florida
6 hours 21 mins
I always add a couple hours since I'll be driving slower with a TT.
There are state ran rest stops (can probably google them) along 95 in most states. As well as, Fly J, and Pilot truck stops are other free places along 95.
Best of luck.
This site is kind of cool.
http://www.i95exitguide.com/restareas/