We are planning a first big trip with our '09 Phaeton. We leave in July from Tampa headed to Twin Creek Resort in Gatlinburg. Any advice from you 'ol timers out there?
My personal preference is for a US route that roughly parallels the shortest Interstate route. Those roads often are in really good shape and have minimal traffic.
The only problem with that is going through big towns. There I hop on the Interstate due to time and ease of navigation.