Google Maps gives me 2 choices - 126 the whole way, or 58 (with the Crescent Cutoff). The later is 30 miles and 26 minutes longer. The 58 route uses a slightly lower pass, and over all might be straighter. But otherwise the choices are similar.
If you have the time, a slightly longer route using Cascade Lakes National Scenic Byway is worth considering. This heads west from Bend, past Mt Bachelor, views 3 Sisters, and past various lakes and lava flows.
In the west US20 looks twistier than OR126 (though I've only driven the latter).
Don't forget that map programs just calculate the fastest route. They won't differ much on distance, but times will differ depending on their speed estimates.
When I tweak the GM route to use 242, I see that is a bit shorter, but quite a bit slower. Evidently GM is using a lower speed estimate for this road. Bing is 30 minutes faster on this route. Evidently some human has told GM to use a slower speed on this leg, or it actually takes the road geometry (curves, grades) into account.
