Finding safe location for boondocking

I am assuming you are talking about rural areas. First, anyone can be a victim almost anyplace. I try to just be vigilent and observant. If I feel uncomfortable I wouldn't camp there. Are other campers in the area? Do I feel comfortable around them? It is just like driving in a different town that I haven't been in before. If I walk into a store am I in my comfort zone? I don't think it is any one thing.