The road to the park are great, minus a couple of tolls. Inside the park is another story. Section 1 is for tents and popups. Do not try to fit a trailer over 20ft in there. Section two is the pet loop. It's road is curvy with lots of trees, but I've seen large toy haulers go down there without hitting anything. It's sites sizes vary. Section 3 is non pet RV loop. It's roads are straight but the water sites are on the short side. Their website shows you the dimensions and a photo of each site. Some sites have tricky approaches as they try to preserve the trees and there are a lot of them. There are raccoons, but the only time they were a problem for us was right after a tropical storm evacuation. We checked in the day they reopened and the place was dead for a couple of days so the coons converged on the few campers that was there.
That being said, Ft Desoto is our favorite local campground and is very popular with the fishing, beach and paddling crowds.