Be super alert when driving the border with Mexico... Especially parking at the Rest Stops... Lots of info on-line about this... Could be lots of People traffic in the middle of the night. I10 can also have Border Patrol Inspection stops that can show up anywhere along this route depending on their alert status.
Also we always shut down our Internet devices when we are close to the borders to prevent roaming fees from a foreign country etc...
I would not venture far from I10 in these areas. You might get into a trafic lane heading for the border and have no way to turn around. You might get back OK but your RV may not...
just some of my thoughts for us travelers that are not all that familiar with this area.
Roy Ken