2017 F250 gas performance upgrade

Being a '17, Ford has locked the ECM from changes in closed loop operation. Meaning, that below 3000 RPM, a tune will effect nothing. Above 3000 rpm, a tune can get a little more aggressive with timing and improve fuel trims. Biggest bang for the buck is to reduce restrictions on the intake (open the airbox and tubing) and exhaust (cams, headers, or shorty headers if in an emissions controlled region).

Cheapest and easiest is to drive aware and be in a gear to be above 3000 rpm when needed.