My preference would be to buy a slightly used motor home, so I wouldn't waiting to buy the new Ford model. I ended up buying a used one with the 19" tires and haven't had a problem and it works well for our traveling i.e. we're not full timers. I can see trying to get one with the 22" tires if possible, but I'd be more concerned about floor plan, quality, and cargo capacity if looking for a used unit. If buying new, I'd go for the 22" tire as long as the cargo capacity was is adequate, based upon the reputation for better ride quality with the larger tire.