Yep. What the guy above said. I have the e450 2017 thor 23u, sort of the Chevy vs GMC . Our coaches nearly the same. Towed my Rubicon all thru utah, Sierra and Wyoming this summer. Not so sure it's the weight of the motorhome vs the wheelbase but you do feel it more than I did on my 32,000 lbs 40 ft diesel. If your towbar and hitch are tight, little slack will feel better. Stops fine, towed fine. Used the auxiliary brake system.also hung a dirt bike off back of the jeep. No worries, my suspension is stock tho.
With e450 you get 14,500 lbs gross. I doubt I'll be able to overload it with what I carry. Supposedly bigger brakes and a little more steel in frame rails, springs.