At some point on a long steep grade you're going to have to give it some hard breaking to get the speed back down to a comfortable level. Hard braking at 4000 RPM to get the engine under 3000 RPM are safe numbers. It will build up a some heat but much less than riding the brakes for a long time. The disks on an F53 are pretty big and will bleed off the heat quickly if you give them time to do so. Riding the brakes won't.
Don't worry about the high engine RPM the ECU will protect the engine to the point I think of even up shifting to a higher gear but I've never read any postings of that occurring. My engine cover was sound and heat insulated by the prior owner which helps a bunch to hold down the engine noise.
My coach is a bit lighter at 15,000 pounds but I've found the tow/haul will hold speed pretty well even with 3K Lbs. of Honda Accord pushing on the back end but I haven't been west of the Mississippi River as yet. Came down I40 in western North Carolina two summers ago. Long steep grade east of Ashland with a mandatory stop for all trucks prior to the decent. Used the brakes at the top to get my speed down to 50MPH which caused the transmission to down shift and the power train held me at no faster than 55 all the way down. RPM was up around 4K but OK for the high revving V10. At the bottom hit the cruise resume button and went on my way never touching the brake or accelerator. Had the toad brake indicator flicker a few times on the decent.