2000 Four Winds on 1999 E350 chassis w/ V10, purchased used in 2010.
We first noticed an issue just after we bought it. We stopped to get. bite to eat on the way home. Upon attempting to restart, all it would do was crank. Once I shut the key off, then back on, would it start.
Odd.
One time on a little backroad, it simply died. It restarted ok.
Odd.
Off and on afterwards, it would pull the same stunt - a start or restart would crank, but not start. Off/on cycle always worked.
Odd.
One cold January day, I attempted to conduct my storage monthlies. At or around the first of the month, I would start the engine, and occasionally drive it for a few miles. The monthly of Jan '13, it would not start, no matter what I did.
Really odd.
After evaluating the issue, we found the fuel pump had failed. I purchased a new one, then set about emptying the fuel tank. I always keep it full over winter in case we need to use the unit in an emergency... Yes, 55 gallons worth.
Original story here:
Failure & replacement of fuel pump on E-350 and the subsequent fuel pump teardown:
E-series fuel pump teardown (with pics!) We were very grateful it did not strand us on the road. It very well could have.
After the replacement, it never failed to start. A friend now owns that unit; he stores it in our barn, and as such, I still do my basic monthlies on it (check batteries, start engine/generator) but he buys the fuel & takes care of his repairs as he sees fit.