It is of course guesswork what is wrong until the problem is found.
I would probably start with checking grounds. With everything off, an ohmmeter should show a short circuit between the socket shell/ground line and the frame of the motorhome. (It'll probably be necessary to use a long lead on the meter to get to a good frame ground.) With that many lights on different circuits failing simultaneously, the ground connection seems to me like the main thing that is likely common to them all.
If the wiring runs externally within the frame rails, it might be worth inspecting it for damage, possibly from critters chewing on it.