I used to be engineer too (EE - not tire) and sorry ... but in all due respect I guess I'll have to claim "pure emotion" on this one.
In My Humble Emotional Opinion I just cannot buy that a tire that can hold off higher burst pressure isn't also more tougher/rugged/robust when used at pressures below it's maximum. It's not intuitive at all that higher pressue hold-off doesn't result in superior strength of materials. I learned a long time ago when I was an engineer - when experimental data supposedly based on physical laws didn't add up with thought-filled intuition - that something was most likely Rotten in Denmark somewhere.
However, I'm open to a dramatic change in my intuition. What I DO KNOW is the offroad crowd (and Expedition Vehicle manufacturers) always strive for high ply ratings on their tires regardless of how heavy the vehicle is. Those offroad guys of course even air-down their tires for improved grip .... but always stick with high ply ratings for terrain ruggedness.
Hence ... I would feel more secure when we're off-road rock-hounding if our Class C tires were rated Load Range G instead of Load Range E, even though our RV's corner weights are way below Load Range E maximum weights when using 80 lbs. of pressure in the rear duals and 65 lbs. of pressure in the front singles.