Can the wife do part of the driving? Does the moho have any handling issues at all (truck wind response, wandering, etc)? If it drives right, it'll be a lot less tiring. If the kids can stand it, you'll make better time staying in truck stops, WM's, and rest areas some nights... no lost time on drive to CG, check in, set up, and drive back to the route.
One more hint... don't linger to see the sights in the first & last two or three days. You'll get around to that later. Do nothing but haul tail those days.
Jim, "I was never as good as I used to be."