It all depends on how quickly you want to get to Florida. Time your approach to city's along your route to avoid commute traffic. Drive three hours and have a snack and pit stop; (smell the flowers),switch drivers & enjoy the change of scenery. A small break from driving does wonders for everyone present in your rig. Leave early prior to sun-up on the first day and stop for supper and hang out at the camp site. Go for a walk, get your sleep and do the same thing the following day. Arrive fresh and relaxed at your Florida destination. You are able to drive 9.5 hrs at 60MPH with an average of 50MPH with pitt stops etc. This calculation will give you 480 miles on the first leg of you journey. From Cleveland to Fort Lauderdale is 1224 miles or 18 hours of driving at 50 MPH avg. Do the 9.5 hr per day and you will be basking in the Floridian vitamin C.