Your profile isn't complete so we don't know exactly what you're driving, but I'm going to make the assumption that a 40' Tiffin has air brakes and a supplemental braking system (and you know how to use it). So as long as you use some common sense, you won't have any problem. I've been over those roads and you'll see hundreds of other MHs on them.
You should buy the Mountain Directory which goes state by state, highway by highway listing any road grades or sharp corners (for speed considerations) that you should be aware of. It's divided into two books for either eastern or western states.
Mountain Directories Bill