I just got rid if my Toyo Open Country tires which could not handle the stresses put to it by my class b rv. One by one the belts would separate and the tires would start rumbling. Had new Toyos put on under warranty by Les Schwab and they had the rv all over the road swaying and wandering from lane to lane. I said "enough!". To Les Schwab's credit, they returned all my money and installed new Michelin XPS, which I bought, for free. I got a real smoking' deal at $250/tire. Now the rv drives like it should with no wandering and shifting from lane to lane.
Just thought I'd mention my experience because most people talk about tread wear and initial price, while I'm also concerned about those issues, proper handling is also very important.